Could MRSA be responsible for AAV?

[mrtmeo]

There seems to be a link between MRSA and ANCA Associated Vasculitis.
Microscopic polyangiitis triggered by recur... [Int Urol Nephrol. 2010] - PubMed - NCBI

[mrtmeo]

Found this interesting perspective on the pathology of GPA and MPA
ANCA vasculitis: to lump or split?

[Wegetarian]

I don't think its responsible per se, but from what I heard of it could trigger a re-lapse. I had Staph. Aureus in my nose when I got dx'd. I thought they took care of it, but they checked if I had it when I was in the hospital and the result came back positive. They wanted to check it out due to the reason that it could trigger wegs. At least that is my understanding. I don't think all weg's have been tested positive for Staph. Auresus though, so its not like it would be the cause of it.

[mrtmeo]

My mom had MRSA colonized in her nares.
I did 100:1 ratio of distilled water to 5% Lugol's iodine with baking soda in a neti pot for 3 days and she was negative for MRSA.
Her WBC dropped from 12,000 down to 6,000.

[mrtmeo]

There sure seems to be a big correlation between weg's and mrsa.
Effectiveness of Rituximab in Severe Wegener?s Granulomatosis: Report of Two Cases and Review of the Literature

http://www.ncbi.nlm.nih.gov/pubmed/24827750

[annekat]

I don't have time to read the links right now but know there has been discussion of this on here, and I specifically remember talk of colonization of s. aureus in the nasal cavity/sinuses and it triggering relapses. You might try a search of the archives on MRSA, s. aureus, and also Bactrim, which was mentioned as being effective against these bacteria as well as the ones that cause pneumonia in immunosuppressed people. I think the implication was that many people are carriers of colonized MRSA (or s. aureus, sort of the same thing?) without knowing it, and Bactrim may extend remission by fighting off this bug so it doesn't trigger flares. May be a simplistic explanation, all that I'm capable of right now, and I may be remembering details wrong. Others know more and can talk about it better.