I did not have detectable antibodies after my first 2 vaccine doses, either. An article from a few months back found that something like 25% of patients on Rituxan did produce antibodies after their third dose (I am not entirely sure about that number—I couldn’t find the article, so take with a grain of salt.)

Anyway, wound up getting COVID about 1 month ago. I contacted my rheumatologist before my test result even came back. He saw it the next morning and I got monoclonal antibodies that same day—sotrovimmab, which is thought to be effective against Omnicron. I am incredibly lucky to get my care (and work at) a teaching hospital, and fortunately I recovered without severe illness and without giving it to any of my close contacts.

We need to be careful, but there’s plenty of hope, too. Stay safe, everyone!