I was just wondering if anybody has any symptoms after their infusions of Rituxin. It seems to get me down a few days later and can last up to 4-6 weeks. I get extremely tired and can barely get out of bed. I had the infusions twice last year and just had one 2 weeks ago. It seems to have gotten worse. I'm off right now because I had a total knee replacement and am recovering from that but was doing great until my infusion. I talked with my Rheumy Dr and he seems to think its all in my head. I know its not. Anyone else have these symptoms?