Hello Donna,
It's true that alcohol and mtx don't mix well. The combination - especially excessive (a term that has different definitions) alcohol - can mess up the liver. I'm more of a beer drinker, so I've been able to accommodate with non-alcoholic beers. My favorites are Clausthaler and Kaliber. Unfortunately, non-alcoholic wine is just grape juice. I drink one or two glasses of wine with dinner perhaps once a month or so with no ill effects. The UK mtx protocol is more liberal with alcohol than the US protocol.
I take my mtx on Wednesday (3 pills in am and 4 in pm). I am a little tired on Wednesday and Thursday, but it doesn't interfere with my normal activities. That's the only side effect I've experienced.
I take 1 mg of folic acid daily to prevent hair loss. Seems to be working, although my hair is a little coarser now.
Pete
dx 1/11
"Every day is a good day. Some are better than others." - unknown
"Take your meds as directed and live your life as fully as you can." - Michael Chacey, MD
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