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Thread: Blood Test - CD19 or CD20

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    Default Blood Test - CD19 or CD20

    I had blood work done after the completion of my Rituxan. It was called CD19 or CD20 - the results just say not identified. I believe the test is checking for B cells.
    Has anyone else had this blood test?

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    No, never had that test. How were your results of that test?

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    I am waiting for my Mayo dr to call me and explain it. The nurse of my pulmonologist here in my hometown said the test just read not identified, she wasn't sure what that meant and faxed it to Mayo.

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    B cells have different proteins on their surfaces that enable them to function, and one of them is called CD20. Because rtx is an antibody to CD20, it binds to CD20 and this kills the B cell. Measuring CD20 shows how well the rtx treatments wiped out your B cell population.

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    Oh thanks Sangye, I think I asked you about this blood test a while ago and I called it something else, oops!

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    Reviving this thread to see if anyone has more information.
    I just had this test done (4 weeks post last rituxan treatment) and the results came back all zeros. No cd19 b cells and no cd20 b cells.
    Is this the desired result? Very little information available in layman's terms and Dr's explanation was as clear as mudd.

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    That's the desired result. CD 19 and CD 20 are genes found on the surface of B cells. Rituximab destroys all the B cells in circulation, so if you want to measure the efficacy of ritux you can measure the CD19 and CD20 levels. As the B cells start to repopulate, the levels increase, which means the ritux is wearing off.

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    Hi, Sangye! :-) Been a long time!
    Wegener's (​GPA )- dx Apr10, Granulomatous Hypophysitis - dx Apr10, Diaphragmatic Paralysis - dx Feb16, Bradycardia - dx Dec16. (my story)
    Forum Member Map -- world map for you to put a stickpin of where you are located....

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    Newbie got the answer and I learned something already this morning, from none other than Sangye, again.
    Hi Sangye, hope this finds you well. Nice to hear from you.
    Dale
    Dx Aug, 2009 Remission June 2010 until 8/1/2014

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    Quote Originally Posted by Sangye View Post
    That's the desired result. CD 19 and CD 20 are genes found on the surface of B cells. Rituximab destroys all the B cells in circulation, so if you want to measure the efficacy of ritux you can measure the CD19 and CD20 levels. As the B cells start to repopulate, the levels increase, which means the ritux is wearing off.
    WHAT???!! Hi Sangye, hope all is well!
    Knowing how to think empowers you far beyond those who only know what to think. -NdT


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