Complement Factor H helps regulate the complement alternative pathway. Genetically, I have lower levels of Factor H, which makes my complement system become dysregulated and activated. Keeping up with my magnesium, selenium and omega-3 fatty acid requirements helps raise my Factor H and calm my complement system. More research is needed. Complement Factor H could become a new biomarker for WG someday. ​

Plasma complement factor H is associated with disease activity of patients with ANCA-associated vasculitis

"To our best of knowledge, there is a lack of studies on circulating CFH in patients with AAV."

https://arthritis-research.biomedcen...075-015-0656-8