Welcome to the family, Tricia.

C-anca and Pr3, if positive are indicators of wg activity. If they have become higher, it means that the wg is more active. It goes together with what you tell, about not seeing an improvement. I think that it means that methotraxat isn't working enough for you. The higher preds kept your wg less active and now that you are down to lower preds, the wg has becomes more active.

Mtx didn't work for me either.

I think it means that you need to consult with your wg dr. - I hope he is a vasculitis expert - about changing treatment.

For me and for many others - rituximab makes the difference.

Please update us.