I have had RTX infusions since 2013. I think the count is now at 20. I usually have my infusions on a Thursday. I've found that I have a steroid infused insomnia night, the first night. The next day is rough, but mostly resting. Day three for me is the crash day. On that day, I do not want to get out of bed except to eat and go to the bathroom--and I do eat and drink as much as I can tolerate. Once Monday rolls around, I am usually good to go to work full time for the whole week. About 2 weeks after the second infusion (4 weeks from the first one), I have some fatiguing days, but they are just days of feeling run down and tired, nothing more.

That's my experiences.

Mike