Hi Trionic

All of the studies that I have read advise not to takefolic acid (folate)on the same day as MTX
Others say not to take it within 24 hours either side of taking MTX, and again others say, not to take within 12 hours either side of MTX

Everyone has different ideas, but I have never heard of 3-5 hours after

If your liver is so affected, can your specialists not put you on to a different medication and drop MTX altogether?