Methotrexate tablets or injectable?

**ticklytoes** · 12-31-2009, 05:43 PM

My rheumy wants me to try the inj mtx to see if it will cause better results since its absorbed better...anyone have any info about this? Has anyone switched from tabs to injectable form and seen better results? Nicole

**jola57** · 12-31-2009, 05:46 PM

My rheumy gave me the tablet form since it is the easiest, if they wouldn't work then I would have the injections.

**deb** · 01-01-2010, 03:00 AM

I have only taken the injections but have not experienced the nausea and tiredness others have noted. I have not noticed any additional side effects that do not seem to be from the predizone. Does anyone have these issues with the injections or does it seem to be only those taking tablets?

**Sangye** · 01-01-2010, 03:05 AM

I was on the weekly injections for about 2 months--transitioning from cytoxan. I don't remember feeling nauseous or tired. I felt much better on it than the cytoxan. But to be honest, I was in seriously bad shape then--still on oxygen, barely able to stand. I don't know if my reaction is useful. I went off it because I developed pneumonia and lung infiltrates-- side effect of mtx.

**Barbara1966** · 01-02-2010, 01:27 AM

For me the deference is only the convenience of the tablets, for the injection I was in recliner for 5 hours in cancer center.
I don't experienced any side effects.

**Sangye** · 01-02-2010, 03:55 AM

Barbara, I wonder if that was for something else? The mtx injection is a simple shot you give yourself at home, not an IV. I'm not aware of IV mtx being used for Wegs. IV mtx is used as a chemo for cancer, since it's given in much higher doses.

**Barbara1966** · 01-02-2010, 05:53 AM

Sangye,
I'm still new in this, my was cytoxen

**Sangye** · 01-02-2010, 05:56 AM

Oh, IV Cytoxan, that makes sense! It's very easy to get all the drugs mixed up!

**Hammy8241** · 06-12-2010, 06:34 AM

Just wondered if Ticklytoes moved to injections and what if any difference/benefits/contra they noticed as I’ve been informed by my consultant we will be discussing whether to move to injections mtx when we next meet. Anyone else?

Just increased pred from 20 to 30mg after failed reduction and yes, I have stopped running and stopped overdoing it Sangye

……..and no, I’ve not noticed any great improvement yet and Yes, I still find Tweety cute!! Sad git or what