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Thread: New potential drug for ANCA-Associated Vasculitis: Bortezomib

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    Default New potential drug for ANCA-Associated Vasculitis: Bortezomib

    I like to stay on top of the potential new drugs that are being developed and I ran across this one: Bortezomib. They tested it on one patient with microscopic polyangiitis and she was able to stay in remission without other drugs for four years (!!). This sounds super appealing to me as I suffer from a relapse & high-dose prednisone--sign me up for any trials of Bortezomib for WG!

    Here's the brief commentary about it:
    Bortezomib in refractory ANCA-associated vasculitis: a new option? -- Novikov et al. -- Annals of the Rheumatic Diseases

    Also, in case anyone is interested and missed it the last time it was posted, there's another new potential drug for WG called Dalazatide. Here's information about that:
    Kineta, University of Groningen Present New, Positive Data for Dalazatide in ANCA Vasculitis, an Orphan Disease | Business Wire
    "Drink your tea slowly and reverently, as if it is the axis on which the whole earth revolves—slowly, evenly, without rushing toward the future. Live the actual moment. Only this actual moment is life." -Thich Nhat Hanh

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    One can only hope for drugs that will permanently put the wegs dog to sleep. This drug seems promising, but it's way too soon to know.

    Thanks for posting this!
    Pete
    dx 1/11

    "Every day is a good day. Some are better than others." - unknown

    "Take your meds as directed and live your life as fully as you can." - Michael Chacey, MD

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    Looks cool. Thanks!

    Know anything about Abatacept?

    Sent from my SM-G925V using Tapatalk
    Best wishes,
    Tom
    ----------------------------------
    2 years untreated. Dx w/ biopsy - 2000
    Tx Plan:

    NUTRITION
    RESTORATIVE SLEEP
    RAISE ANABOLISM
    REDUCE ALL INT / EXT STRESSORS

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    I also hope these new drugs, if they turn out to work for WG, are not as expensive as rituximab! Not holding my breath, though.... somebody's got to pay for all the research and work in developing them. Thanks for sharing this info, in any case!
    Anne, dx'ed April 2011

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