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    Default Nausea - Ctx ?

    Hi just wondering if anyone here has used oral cytoxan and had nausea?

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    Yes I was on 175mg ctx a day the nausea was just part of it, but I had other prescriptions to combat it.

    Sent from my SAMSUNG-SGH-I727 using Tapatalk 2

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    No nausea problem with ctx. I was told to take it on an empty stomach. My wife is convinced my stomach is made of cast iron. ;-)
    Pete
    dx 1/11

    "Every day is a good day. Some are better than others." - unknown

    "Take your meds as directed and live your life as fully as you can." - Michael Chacey, MD

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    I was OK when on it too. The first four months were while I was on high dose pred, so things went by SO fast... (-8
    MikeG-2012

    "You never know how strong you are until being strong is the only choice you have"


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    Thanks everyone.
    I am not sure if her prednisone would have to be increased or not while on a low dose ctx.
    Does anyone know?

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    Quote Originally Posted by mrtmeo View Post
    Thanks everyone.
    I am not sure if her prednisone would have to be increased or not while on a low dose ctx.
    Does anyone know?
    I'm guessing that her inflammatory markers would guide pred dosage.
    Pete
    dx 1/11

    "Every day is a good day. Some are better than others." - unknown

    "Take your meds as directed and live your life as fully as you can." - Michael Chacey, MD

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    Quote Originally Posted by Pete View Post
    I'm guessing that her inflammatory markers would guide pred dosage.
    Her inflammatory markers are:
    Rheumatoid Factor 38 (normal range 1-10)
    Sed Rate 25 (normal range 0-20)
    C-rp <.5 (normal range 0-.8)

    Currently, she is on 5mg prednisone.

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    I'm not sure that "low dose" CTX is used much except for when getting used to the drug or when getting off it and reducing it gradually. I think the amount indicated by body weight is considered the therapeutic amount, and that something like 50-75mg/day would be considered sub-therapeutic unless for a very small person, like perhaps a child. However, I know that I was on 100mg. when my weight indicated 125mg, and I did pretty well. So perhaps it would be the same for your mom.

    As for nausea with CTX, I think I had some, but not to the point of throwing up. Also some dizziness, I think, and a general feeling of malaise and weakness. But then, I was really sick with Wegs. I split the dose between morning and night, though I've read things since saying not to do that. And the pred did perk me up enough to make me want to eat like there was no tomorrow. When I wasn't eating or at the computer, I was sleeping, A LOT, and under these conditions, I got pretty used to the side effects of CTX within 2 or 3 weeks. later, when I went out in public, there was some wooziness when making my way around, and that, too, got better within a few weeks.

    As for whether the docs would want to increase your mom's pred dose with CTX, I guess I'd agree with Pete, and her inflammatory markers don't sound too bad, so maybe they'd leave it as is.
    Anne, dx'ed April 2011

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