Cellcept overload?

[Jaypfei]

Hey all!

Haven't posted a lot as I've felt wonderful and have been enjoying life. Of course my last Rituxan dose was Jan. 2014 and in May had to see a new Rheumy. So far he's been good. He informed me that the disease was finally in a medicated quiet state. He then tried Imuran as a maintainence drug this past June, and I had a dreadful reaction that put me in the hospital and elevated my liver functions for nearly two months!
In August he started me on Cellcept. First 1000mg a day for two weeks, then labs came back great so he doubled the dose....1000mg 2x a day. Last week on September. 11, I had a real scratchy throat. It was strange because it was on my left side. The tonsil was inflamed and the gland on the left side of my neck was swelled up like a walnut. Hubby took me to ER because it was very tender to swallow. Of course I didn't want to go.
They do a throat culture and give me a big shot of Rocephin as well as send me home with ten days of 875mg Augmentin. Well, I went Monday to do labs for both Rheumy and Nephrologist follow up. I see nephrologist yesterday morning and he tells me that I have blood in urine. Back in July it was crystal clear, now I have blood.
Lots of things are going through my head....can this be related to the throat inflammation? Is this the disease, or is this a reaction to Cellcept and the Augmentin?
I have limited Wegs and no current symptoms with sinuses, lungs or ears. I know the possibility is always there for it to affect the kidneys, but I'm just in disbelief at the moment. Neph took second urine sample yesterday as well as blood. I'm currently doing a 24 hr collections and I'm sure I will be on pins and needles till I hear something back. Neph said that my Cellcept should be upped to 1500 2x. He's running all these tests to make sure the initial labs weren't just a fluke. Waiting to hear from Rheumy to discuss upping my dose or the next course of action.
Just wanted to give and update. Yep, I'm a bit concerned, but not going into panic mode until I get test results back.

[Dirty Don]

Be patient patient...smiles...

[Jaha]

I just wanted to ask you if you are taking the cellcept along with antibiotic? I'm on cellcept and when I get an infection I have to quit the cellcept. I was just thinking that it could possibly cause a problem taking both at the same time. All the best to you in getting this resolved.

[RCOSSIO]

A couple of things you be aware but always consult your physician.

Cellcept is recommended up to 2000MG daily but you can go up to 3000MG daily if your doctor feels its best to control the flare. Another thing is the Augmentin may make Cellcept less effective...now I would definitely ask my doctor how taking this antibiotic interacts with Cellcept. Sometimes you may...not always have to increase your prednisone since Cellcept does take time to take effect.

Bring a list of these questions to your rheumy and ask them and also consult with your pharmacist.