I was told yesterday that last week's Gastroscopy showed that I had some thrush (candida) in the oesophagus and in the stomach. I had been given fungilin lozenges to dissolve in my mouth but have now been prescribed something rather more potent as the biopsies showed considerable (moderate to severe) Oesophagitis and gastric reflux. The only symptoms of this to me are chest pains at the moment.
I have a question to other Forum members if they have ever had to take Fluconazole whilst on Pred. I will repost what I posted on the local Wegener's FB forum here in case someone somewhere else has experience with the interactions of these drugs. Below are the details. Thanks for your help

Well here's a new conundrum. I just managed to get the new meds for the Thrush a product called Fluconazole Sandoz 100mg. I am to take 2 tablets day one then 1 daily for 2 weeks. As I want to figure out the best time of day to slot this in given all the other stuff i take I checked it out carefully on the internet. As usual the list of potential side effects is quite hair raising anyway ... I am beginning to get used to ignoring those just printed out the list for Dennis as the majority if you get them require immediate action i.e. another visit to ER. So Dennis can monitor me. LOL some of the "more common" side effects are stomach pain and heart burn. Just what I need an extra dose off.
However what is really frustrating is this drug comes with a huge number of other meds that are contraindicated. Luckily most of them I don't take. I am now thankful I am on Insulin and not oral diabetic tablets for instance. But guess what. Predninsone / Prednisolone is on the list. Furthermore it states on another website that a) the interaction increases the potency of BOTH drugs b) you need to have regular blood tests to monitor the effect and c) the interaction is SIGNIFICANT and requires close monitoring by your doctor. They tell you to make sure you take a list of all vitamins and drugs you take to your doctor. Well I do that for every visit with every doctor I see. But not all of them use the computer to verify. My old GP had a computer system which would warn him the minute he prescribed something that had an issue with what I was already taking and with my medical history. The Gastroenterologist pulled out a book to check the angina tablets she ordered but I didn't see her check the book for this Fluconazole.
Well I was told to take it for 2 weeks. Was not told about any monitoring required. Was told to let my GP manage the Oesophagitis in future. Was not told who would check if the 2 weeks got rid of the thrush. It's not as if I can see it myself, being in my stomach and oesophagus.
So now I am in a fix. Do I just ignore all this given that I ignore a lot of warnings on packages as I realise mainly it's there to protect THEIR hide in case of litigation. Or do I put off taking it and double check with WHOM??? Rheumy??? GP ???? both of which have already prescribed stuff contraindicated for people on some of the meds I am on (one example being the MTX and the Bactrim) so chances are they may not even know this level of detail.
Question here ... has anyone else taken Fluconazole and Pred together? I am not too worried about it increasing the potency of the Pred for 2 weeks. Guess I am used to higher doses of that stuff. Not sure though how nasty the Fluconazole is likely to get as a result of the pred and 20 mg a day of pred is still considered a fairly high dose. I'll post this on the global forum as well just in case someone there has some info. Guess one option is to go back to the lozenges for now and wait until I have more info from the Rheumy at least, if I can get a hold of him.