I have some questions about my treatment and am wondering if it is working the way it should be. I was diagnosed with WG last fall with a PR3 antibody of 318 plus nasal and ear symptoms. I started 10 mg methotrexate weekly and 30 mg prednisone which tapered down to 5 mg daily over 4 weeks. My PR3 score went down to 158. For the next 6 weeks I dropped the prednisone down to 2.5 mg daily. My PR3 score went down to 130. Although the score is falling, the inflammation in my ears has not gone away yet and I still experience a runny nose when I eat (Gustatory Rhinitis).
My rheumatologist thought we should bump up the MTX a bit so I am now on 15 mg weekly. Then, out of the blue my knee started hurting like it did when this all began last fall. I guess this is called a "flare"? I increased the pred back to 30/20/10 mg over the last couple of weeks. That seemed to fix the knee but the ears and nose seem unaffected.
I was just wondering if this was typical of other peoples' experiences with this type of treatment? Should I ask my rheumatologist to modify dosages or try new medications? Any insight would be much appreciated. Thanks.
Keith
Bookmarks