At the absolute worst, I had a session of vomiting, where I counted 18 (!) eruptions in a row. I was so tired and sore toward the last that I was crying. I hope your wife continues to improve, that the vomiting is brought into control. There are times you can't imagine where the material being brought up came from, or what's next (the stomach???!).
I was stupid about bring it to my doctor's attention, so suffered needlessly in this regard.
Make sure her doctor is aware of the severity of the vomiting and the frequency the next time your wife sees him/her. As mentioned before, if she is at a weight that is right on the line of requiring more or less Cytoxan, her doctor may have decided on the higher dosage to determine how heavy a dose she can handle, with the expectation that issues like vomiting would help him/her adjust the dosage to a level adequate to bring her WG into line.
(p.s. all I had to do to trigger vomiting was to take my medication with cold water; like your wife, I was trying to drink lots of water, as directed, and used a 28 oz.[roughly 0.95 liter] glass; lukewarm water helped for pill-taking for me)
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