Hi Cindy,
Are you taking your ctx in a single daily dose or spreading it out over the course of the day? When I was taking 150 mg/day (my largest dosage), I would take a pill upon arising (before breakfast), at mid-afternoon, and about an hour before bedtime. I always drank a large (16 oz) glass of water with each pill. I never felt bad on ctx, but did start developing some urinary symptoms after I had been on it for about 14 months. These symptoms disappeared when my rheumy changed me over to mtx.
Hope this is helpful.
Pete
dx 1/11
"Every day is a good day. Some are better than others." - unknown
"Take your meds as directed and live your life as fully as you can." - Michael Chacey, MD
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