Hi,
I've been on mtx 20mg/week for over a year now and i take it on saturday night but lately i am experiencing extreme tiredness the following day (sunday) and a little tired on monday. My blood works looks good (actually went this week and i had normal results). So i was told 3 different things that i could try. I can split my 20mg into 2 dose of 10mg withing 24h and see if that work. Apparently that dextromethorphan (DM like robitussin DM without acetaminophen or ibuprofen) can help to reduced the side effects of mtx (extreme tiredness in my case). taking this dextromethorphan before taking mtx can significantly reduce those side effect. I've seen some comments about this on internet and seems like it works for some people.
I was told to take more vitamin A as well.
any thoughts?
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