LDN (Low Dose Naltrexon) and Wegener's?

[mrtmeo]

I know this is an old post, but the info is very interesting.
Here is a study showing autoimmune disease in rats show very low endorphins controlled by the hypothalmus
Hypothalamic beta-endorphin concentrations are decreased in animals... - PubMed - NCBI

It sure sounds like LDN could have some benefit by gradually increasing the dose (starting extremely low) so that the body will upregulate endorphins gradually to help the immune system function properly.
I wonder if this would be of more benefit once someone is in remission?

This explains why exercise improves health problems because it increases endorphins.

[mrtmeo]

This is interesting.

Enkephalins and endorphins as modifiers of the immune system: present and future.
Enkephalins and endorphins as modifiers of the immune system: prese... - PubMed - NCBI

[mrtmeo]

This is encouraging although it is for crohn's disease and not vasculitis.
None were allowed infliximab, unfortuneatly, but any other medications they were on more than 4 weeks prior to the study were allowed.
A remission of 67%,after 3 months, is pretty impressive, but not sure what drugs they were on to start with.
http://www.nature.com/ajg/journal/v1...g2007152a.html