Anybody taking Bactrim + Methotrexate?

[Jack]

There was at least one trial run on Bactrim to prevent relapse which lasted for two years. Duing this time 82% of the Bactrim group remained in remission against 60 % of the placebo group. The conclusion to this report speculates that infections trigger relapse and this is why Bactrim helps.

[Sangye]

Can you find that study Jack?

[Minneapolismark]

By the way my doctor says the combination of MTX and Pred are making me paranoid, but I just think he's just saying that because he's out to get me.

[Sangye]

I don't want anyone to get the wrong idea about my last comment. Some Weggies have demonstrated that they need to stay on Bactrim to avoid infections and/or Wegs flares. In that case, the benefit outweighs the risk. My comment was directed at doctors who put Weggies on Bactrim indefinitely, without even seeing how they do without it.

[Minneapolismark]

I'd have to dig this up, but there was a study in one of the medical journals that indicated a persistent sinus infection could lead to recurrence and flareup. If so, then Bactrim would be a good idea to prevent or mitigate a sinus infection. This could be one of the reasons why Bactrim may mitigate recurrence. IMHO.

[Jack]

Trimethoprim-sulfamethoxazole (co-trimoxazole) for... [N Engl J Med. 1996] - PubMed result

MMS: Error

Some other interesting stuff here - co-trimoxazole wegener's - PubMed result

Unfortunately most of these are just abstracts.
Note: in the UK Bactrim is called Co-Trimoxazole.

[Sangye]

Bactrim is also called Septra in the US. Apparently we can't handle drug names over 2 syllables.

[drz]

Trimethoprim-sulfamethoxazole (co-trimoxazole) for... [N Engl J Med. 1996] - PubMed result

MMS: Error

Some other interesting stuff here - co-trimoxazole wegener's - PubMed result

Unfortunately most of these are just abstracts.
Note: in the UK Bactrim is called Co-Trimoxazole.

Is this drug contraindicated with Imuran?

[Minneapolismark]

Trimethoprim-sulfamethoxazole (co-trimoxazole) for... [N Engl J Med. 1996] - PubMed result

MMS: Error

Some other interesting stuff here - co-trimoxazole wegener's - PubMed result

Unfortunately most of these are just abstracts.
Note: in the UK Bactrim is called Co-Trimoxazole.

THANKS Jack, this is very helpful. I must be one of the few who can't tolerate Bactrim.

[ScreaminMeanie]

There was at least one trial run on Bactrim to prevent relapse which lasted for two years. Duing this time 82% of the Bactrim group remained in remission against 60 % of the placebo group. The conclusion to this report speculates that infections trigger relapse and this is why Bactrim helps.

I recall reading that in a couple of places, too. That's one of the reasons I wanted to stay on it.