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Thread: Has anyone done the desensitization to sulfa procedure?

  1. #11
    renidrag's Avatar
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    Wow, I never knew of the relationship of Bactrim and Warfarin. I was on both for months, I guess that is why my blood INR was checked weekly.
    I thought it was weird at the time, huh, they knew what they were doing.
    Dale

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    Quote Originally Posted by marta View Post
    Hi again, I did consider trying it but my doc at the time decided against it as there was too much on the plate to go through that as well. We also have a small hospital and I probably wouldn't feel super safe in case something went wrong.

    So I haven't been on Bactrim but I'm on Dapsone instead. I've been taking it every day since diagnosis and no ill side effects. It's a pill so I pop it with all my others. I know that Bactrim has a mysteriously positive side effect on those with sinus involvement - which I do - so I was kinda bummed that I couldn't take it, but like I said the dapsone has been fine. I think those are the three choices. Bactrim, Dapsone and the pentamadine nebulizer. Maybe you could ask if you can try Dapsone. They wanted to take me off it at one time when my liver was acting up but then using Sangye's words of wisdom I sleuthed my liver issues to active disease and not the Dapsone - which has been proven to be the case since then.

    Hope this helps.
    Situation here is similar. already been through Dapsone. It caused some weird blood disorder which increased my anemia. The hematologist told me it was causing the end of my red blood cells to break off but this cleared up after I stopped the Dapsone. Allergic to sulfa so no other choices.

    The desensitization procedure sounds simple. You take one drop first day, two drops second day, three the third day etc till you get up to 21 drops which is equivalent to one regular Bactrim pill. They put the drop in a small glass of water to make it easier to take. Ideally you should have no reaction. Any reaction is not good unless very mild. My reaction on second day was considered a bad sign and I had another important medical appointment in another town two hours later so thought it best to postpone it till later. I hope I can try it again. I did take an Cetirizine allergy med before these treatments otherwise it might have been worse.

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