I have just got the instructions out of a new box of Methotrexate and in bold print it states the following:-
NSAIDs (non-steroidal anti-inflammatory drugs) e.g. ibuprofen, indomethacin or asprin (for relief of pain or inflammation) including any preparations of these bought without a prescription.Taking theses products together withMethotrxate Tablets can increase its toxic effects.
So if you are on Methotrexate then it is a no no to take asprin or ibuprofen. I just noticed that I must not get pregnant or breast feed ........ damn!
Jim
You give but little when you give of your possessions. It is when you give of yourself that you truly give. Kahil Gibran